Preheat oven to 350 degrees Fahrenheit.
In a large bowl, whisk together flour, baking powder, baking soda, sugar, and salt.
Using a pastry blender (or a fork), incorporate butter into dry ingredients, creating pea-sized chunks of the mix.
Fold in buttermilk until thick dough forms. If you don't have buttermilk handy in the fridge, check out this Buttermilk Substitute that works great for recipes!
Lightly flour a clean surface and place dough onto surface. Knead dough 6-10 times. You don't want to over knead biscuit dough, but want to at least incorporate a little more flour into the dough to make it easier to shape into biscuits.
Cut dough into 2-3 pieces, rolling each piece into a rectangular shape about 1/4-1/2 inch thick.
Stack the rectangular pieces of dough on top of each other. Cut 2-3 inch round biscuits out of the dough. Place cut out biscuits onto greased baking sheet.
Bake 10-15 minutes or until golden brown on the bottom.